The Phosphoinosotide 3-Kinase Catalytic Subunit p110α is Required for Normal Lens Growth
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چکیده
منابع مشابه
The Phosphoinosotide 3-Kinase Catalytic Subunit p110α is Required for Normal Lens Growth
PURPOSE Signal transduction pathways influence lens growth, but little is known about the role(s) of the class 1A phosphoinositide 3-kinases (PI3Ks). To further investigate how signaling regulates lens growth, we generated and characterized mice in which the p110α and p110β catalytic subunits of PI3K were conditionally deleted in the mouse lens. METHODS Floxed alleles of the catalytic subunit...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2016
ISSN: 1552-5783
DOI: 10.1167/iovs.16-19607